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1

Ascorbic acid: Chemistry, biology and the treatment of cancer

Du, Juan, Cullen, Joseph J., Buettner, Garry R.

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

2

Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio-Chemotherapy While Protecting Normal Tissue

Schoenfeld, Joshua D., Alexander, Matthew S., Waldron, Timothy J., Sibenaller, Zita A., Spitz, Douglas R., Buettner, Garry R., Allen, Bryan G., Cullen, Joseph J.

Journal:

Seminars in Radiation Oncology

Year:

2019

Language:

english

File:

PDF, 1.07 MB

english, 2019

3

Titanium(IV) and Vitamin C: Aqueous Complexes of a Bioactive Form of Ti(IV)

Buettner, Katherine M., Collins, Joseph M., Valentine, Ann M.

Journal:

Inorganic Chemistry

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

4

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy

Doskey, Claire M., Buranasudja, Visarut, Wagner, Brett A., Wilkes, Justin G., Du, Juan, Cullen, Joseph J., Buettner, Garry R.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.40 MB

english, 2016

5

The check is in the mail: piloting a novel approach to Chlamydia trachomatis testing using self-collected, mailed specimen

Buhrer-Skinner, Monika, Muller, Reinhold, Bialasiewicz, Seweryn, Sloots, Theo P., Debattista, Joseph, Gordon, Rose, Buettner, Petra G.

Journal:

Year:

2009

Language:

english

File:

PDF, 878 KB

english, 2009

6

Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells

Brandt, Kristin E., Falls, Kelly C., Schoenfeld, Joshua D., Rodman, Samuel N., Gu, Zhimin, Zhan, Fenghuang, Cullen, Joseph J., Wagner, Brett A., Buettner, Garry R., Allen, Bryan G., Berg, Daniel J., S

Journal:

Year:

2018

Language:

english

File:

PDF, 249 KB

english, 2018

7

Affinity purification of fibrinogen using a ligand from a peptide library

Deborah B. Kaufman, Marc E. Hentsch, George A. Baumbach, Joseph A. Buettner, Christopher A. Dadd, Ping Y. Huang, David J. Hammond, Ruben G. Carbonell

Journal:

Biotechnology and Bioengineering

Year:

2002

Language:

english

File:

PDF, 191 KB

english, 2002

8

Affinity purification of von Willebrand factor using ligands derived from peptide libraries

Ping Y. Huang, George A. Baumbach, Christopher A. Dadd, Joseph A. Buettner, Barbara L. Masecar, Marc Hentsch, David J. Hammond, Ruben G. Carbonell

Journal:

Bioorganic & Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 1.12 MB

english, 1996

9

Chromatographic resolution of tryptophan enantiomers with l-Leu–l-Leu–l-Leu peptide: Effects of mobile phase composition and chromatographic support

Deborah B Kaufman, Timothy Hayes, Joseph Buettner, David J Hammond, Ruben G Carbonell

Journal:

Journal of Chromatography A

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

10

Alkali-resistant Hæmoglobins in Prosimian Primates

BUETTNER-JANUSCH, JOHN, TWICHELL, JOSEPH B.

Journal:

Year:

1961

File:

PDF, 115 KB

1961

11

Regulation of pancreatic cancer growth by superoxide

Juan Du, Elke S. Nelson, Andrean L. Simons, Kristen E. Olney, Justin C. Moser, Hannah E. Schrock, Brett A. Wagner, Garry R. Buettner, Brian J. Smith, Melissa L.T. Teoh, Ming-Sound Tsao, Joseph J. Cull

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 428 KB

english, 2012

12

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann, Joseph M. Gozgit, Anne Schroeder, Adam Sheehy, Ralf Buettner, David Proia, Claudia M. Kowolik, Hong Xin, Brian Armstrong, Geraldine Bebernitz, Shaobu W

Journal:

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

13

Inhibitors of Hydroperoxide Metabolism Enhance Ascorbateinduced Cytotoxicity

Juan Du, Kristen Olney, Jordan Witmer, Thomas Van't Erve, Zita Sibenaller, Garry Buettner, Joseph Cullen

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

14

Tempol Inhibits Pancreatic Cancer Cell Growth

Juan Du, Kristen Olney, Hannah Schrock, Justin Moser, Brett Wagner, Zita Sibenaller, Garry Buettner, Joseph Cullen

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

15

Comment on “Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer,” i.e., all we are saying is, give C a chance

Joseph J. Cullen, Douglas R. Spitz, Garry R. Buettner

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 173 KB

english, 2011

16

A Phase I Clinical Trial of Ascorbic Acid and Gemcitabine for the Treatment of Metastatic Pancreatic Cancer

Jessemae Welsh, Brett Wagner, Pamela Zehr, Daniel Berg, Thorvardur Halfdanarson, Nelson Yee, Kellie Bodeker, Sundershan Bhatia, Garry Buettner, Mark Levine, Joseph Cullen

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 82 KB

english, 2011

17

Manganoporphyrin MnTMPyP Enhances Ascorbate-Induced Cytotoxicity in Pancreatic Cancer Cells Via Generation of H2O2

Malvika Rawal, Samuel R. Schroeder, Juan Du, Brett Wagner, Garry R. Buettner, Joseph J. Cullen

Journal:

Free Radical Biology and Medicine

Year:

2011

Language:

english

File:

PDF, 54 KB

english, 2011

18

Chemically derived peptide libraries: A new resin and methodology for lead identification

JOSEPH A. BUETTNER, CHRISTOPHER A. DADD, GEORGE A. BAUMBACH, BARBARA L. MASECAR, DAVID J.H. HAMMOND

Journal:

Chemical Biology & Drug Design

Year:

1996

Language:

english

File:

PDF, 4.74 MB

english, 1996

19

RNA recognition by an isolated α helix

Ruoying Tan, Lily Chen, Joseph A. Buettner, Derek Hudson, Alan D. Frankel

Journal:

Year:

1993

Language:

english

File:

PDF, 2.17 MB

english, 1993

20

Hepatic Cannabinoid Receptor-1 Mediates Diet-Induced Insulin Resistance via Inhibition of Insulin Signaling and Clearance in Mice

Jie Liu, Liang Zhou, Keming Xiong, Grzegorz Godlewski, Bani Mukhopadhyay, Joseph Tam, Shi Yin, Peter Gao, Xin Shan, James Pickel, Ramon Bataller, James O'hare, Thomas Scherer, Christoph Buettner, Geor

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 2.74 MB

english, 2012

21

The Role of Transition Metal Ions in Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Du, Juan, Buettner, Garry R, Cullen, Joseph J

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

22

Pharmacological Ascorbate Enhances Chemo-Radio-Sensitization in Brain and Lung Cancer

Allen, Bryan G, Sibenaller, Zita A, Cullen, Joseph J, Buettner, Garry R, Welsh, Jessemae L, Wagner, Brett A, van't Erve, Thomas J, Buatti, John M, Carlisle, Thomas L, Smith, Mark C, Walsh, Susan A, Ba

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 182 KB

english, 2012

23

Ascorbate Is a Radiosensitizer in Pancreatic Cancer

Welsh, Jessemae L., Du, Juan, Sibenaller, Zita A., Kalen, Amanda L., Wagner, Brett A., Allen, Bryan G., Spitz, Douglas R., Goswami, Prabhat C., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 192 KB

english, 2012

24

Maintenance of Cancer Cell Bioenergetics during Cell Death Processes Following Ionizing Radiation

Wagner, Brett a, Welsh, Jessemae L, Van't Erve, Thomas J, Schroeder, Samuel R, Sibenaller, Zita a, Doskey, Claire M, Du, Juan, Cullen, Joseph J, Buettner, Garry R

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 78 KB

english, 2013

25

Quantitating Weak EPR Spectra of Free Radicals in Biological Samples

Schroeder, Samuel R., Wagner, Brett A., Rawal, Malvika, Doskey, Claire M., Cullen, Joseph J., Buettner, Garry R.

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

26

Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1α in pancreatic cancer

Sibenaller, Zita A., Welsh, Jessemae L., Du, Changbin, Witmer, Jordan R., Schrock, Hannah E., Du, Juan, Buettner, Garry R., Goswami, Prabhat C., Cieslak, John A., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 1.95 MB

english, 2014

27

Manganoporphyrins Enhance Ascorbate-Induced Cytotoxicity Selectively in Pancreatic Cancer

Rawal, Malvika, Schroeder, Samuel R., Du, Juan, Welsh, Jessemae L., Sibenaller, Zita A., Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 81 KB

english, 2013

28

Potential of Manganoporphyrins to Enhance the Efficacy of Pharmacological Ascorbate in the Treatment of Pancreatic Cancer

Rawal, Malvika, Schroeder, Samuel R., Wagner, Brett A., Du, Juan, Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 217 KB

english, 2012

29

W1392 Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Cullen, Joseph, Buettner, Garry R., Du, Juan, Levine, Mark

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 86 KB

english, 2008

30

Predicting Plasma Levels of Ascorbate Upon Infusion of Pharmacological Doses

Cushing, Cameron, Wagner, Brett, Cullen, Joseph J, Buettner, Garry R

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

31

The Role of Redox Active Transition Metals in Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Du, Juan, Rawal, Malvika, Moser, Justin C, Olney, Kristen E, Buettner, Garry R, Cullen, Joseph J

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

32

Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer

Moser, Justin C., Rawal, Malvika, Wagner, Brett A., Du, Juan, Cullen, Joseph J., Buettner, Garry R.

Journal:

Year:

2014

Language:

english

File:

PDF, 659 KB

english, 2014

33

The ‘mitoflash’ probe cpYFP does not respond to superoxide

Schwarzländer, Markus, Wagner, Stephan, Ermakova, Yulia G., Belousov, Vsevolod V., Radi, Rafael, Beckman, Joseph S., Buettner, Garry R., Demaurex, Nicolas, Duchen, Michael R., Forman, Henry J., Fricke

Journal:

Year:

2014

Language:

english

File:

PDF, 382 KB

english, 2014

34

Age-Associated Metabolic Reprogramming in Stroma Promotes Pancreatic Cancer Progression

Son, Jyungmean, Sarsour, Ehab H., Xiao, Wusheng, Fussell, Jenna, Wagner, Brett A., Buettner, Garry R., Du, Juan, Cullen, Joseph J., Goswami, Prabhat C.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 32 KB

english, 2014

35

The Addition of Manganoporphyrins and Ascorbate to Standard of Care Chemotherapy Enhances Tumor-Specific Cytotoxicity in Pancreatic Cancer

Cieslak, John A., Strother, Robert, Du, Juan, Rawal, Malvika, Doskey, Claire M., Schroeder, Samuel R., Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 76 KB

english, 2014

36

Intracellular Redox Active Metal Ions Mediate the Differential Susceptibility of Lung and Brain Cancer Cells to Pharmacological Ascorbate

Schoenfeld, Joshua D, Sibenaller, Zita A., Mapuskar, Kranti A., Cullen, Joseph J., Buettner, Garry R., Spitz, Douglas R., Allen, Bryan G.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 33 KB

english, 2014

37

In Vitro Bioenergetic Changes Associated with Ionizing Radiation (IR), Genotoxins and Redox Toxins

Wagner, Brett Alan, Doskey, Claire M, Du, Juan, Cullen, Joseph J, Buettner, Garry R

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

38

The Role of Transition Metal Ions in Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Du, Juan, Wagner, Brett A, Buettner, Garry R, Cullen, Joseph J

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 37 KB

english, 2014

39

Two non-parametric methods for derivation of constraints from radiotherapy dose–histogram data

Ebert, M A, Gulliford, S L, Buettner, F, Foo, K, Haworth, A, Kennedy, A, Joseph, D J, Denham, J W

Journal:

Physics in Medicine and Biology

Year:

2014

Language:

english

File:

PDF, 1.55 MB

english, 2014

40

Rate of Prescription of Antidepressant and Anxiolytic Drugs after Cyclone Yasi in North Queensland

Usher, Kim, Brown, Lawrence H., Buettner, Petra, Glass, Beverley, Boon, Helen, West, Caryn, Grasso, Joseph, Chamberlain-Salaun, Jennifer, Woods, Cindy

Journal:

Prehospital and Disaster Medicine

Year:

2012

Language:

english

File:

PDF, 204 KB

english, 2012

41

Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer

Cieslak, John A., Strother, Robert K., Rawal, Malvika, Du, Juan, Doskey, Claire M., Schroeder, Samuel R., Button, Anna, Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.28 MB

english, 2015

42

Role of labile iron in the toxicity of pharmacological ascorbate

Du, Juan, Wagner, Brett A., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

43

Genetic traits and problems of biological parenthood in two Peruvian Indian tribes

Buettner-Janusch, John, Bove, Joseph R., Young, Nathaniel

Journal:

American Journal of Physical Anthropology

Year:

1964

Language:

english

File:

PDF, 403 KB

english, 1964

44

Regression of Choroidal Metastases From a Bronchial Carcinoid Tumor After Chemotherapy With Cisplatin and Etoposide

Fan, Joseph T., Ortiz, Rafael G., Buettner, Helmut

Journal:

American Journal of Ophthalmology

Year:

1994

Language:

english

File:

PDF, 909 KB

english, 1994

45

Clinical Features and Treatment of Seven Patients With Carcinoid Tumor Metastatic to the Eye and Orbit

FAN, JOSEPH T., BUETTNER, HELMUT, BARTLEY, GEORGE B., BOLLING, JAMES P.

Journal:

American Journal of Ophthalmology

Year:

1995

Language:

english

File:

PDF, 2.00 MB

english, 1995

46

The Role of Pharmacological Ascorbate on Tumor Cell Invasion and Metastasis

Du, Juan, Cieslak, John A., Wilkes, Justin G., Buettner, Garry R., Cullen, Joseph J.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 233 KB

english, 2015

47

Using Quantitative Redox Biology to Achieve a More Universal and Global Bioenergetic Phenotype Analysis

Wagner, Brett A, Doskey, Claire M, Du, Juan, Cullen, Joseph J, Buettner, Garry R

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 199 KB

english, 2015

48

The Selective Toxicity of Pharmacological Ascorbate Is Mediated by Alterations in Iron Metabolism

Schoenfeld, Joshua D, Sibenaller, Zita A., Doskey, Claire M., Mapuskar, Kranti A., Parekh, Kalpaj R., Keech, John C., Cullen, Joseph J., Buettner, Garry R., Spitz, Douglas R., Allen, Bryan G.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 247 KB

english, 2015

49

Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma

Witmer, Jordan R., Wetherell, Bailey J., Wagner, Brett A., Du, Juan, Cullen, Joseph J., Buettner, Garry R.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

50

Repeat readmission following major surgery among patients with employer-provided health insurance

Kim, Yuhree, Spolverato, Gaya, Ejaz, Aslam, Schneider, Eric B., Canner, Joseph K., Buettner, Stefan, Xu, Li, Pawlik, Timothy M.

Journal:

Journal of the American College of Surgeons

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015